Why is vitamin B6 important for your heart and skeletal muscle?



发布日期：2018-02-28
报告题目：Why is vitamin B6 important for your heart and skeletal muscle?
主 讲 人：Thanutchaporn Kumrungsee，Hiroshima University
报告时间：2018年3月5日上午10:30-11:30
报告地点：逸夫楼报告厅 
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讲座主要内容：
Many studies have suggested that vitamin B6 supplementation reduces a risk of heart disease. However, the relationship of vitamin B6 intake and risk of heart disease is controversial, and the underlying mechanisms are not fully understood. Recently, we found that vitamin B6 supplementation in rats had no effect on homocysteine concentrations in the heart tissue, but markedly increased heart concentrations of imidazole dipeptides, such as carnosine, anserine, and homocarnosine. In addition, we found that vitamin B6 also played an important role in the regulation of the imidazole dipeptide homeostasis in skeletal muscle. Taken together with recent reports showing that imidazole dipeptides have crucial roles in heart and skeletal muscle such as antioxidant, pH-buffering, and ergogenic effects, we propose a novel mechanism underlying heart and muscle-protective effects of vitamin B6 through maintenance of imidazole dipeptide levels.
主讲人简介：
Dr. Thanutchaporn Kumrungsee于2015年毕业于日本九州大学，并在食品分析研究室担任一年特别研究员，2016年至今为日本广岛大学食品科学与生物功能部副教授，主要研究方向为具有生活习惯病潜在预防作用的食品功能因子的开发及其相关机理的研究，主持和参与日本MEXT、JST等多项研究课题，发表SCI学术论文三十余篇，为Food Chemistry, Journal of Agricultural and Food Chemistry等国际学术期刊审稿人。